Nicotinamide Riboside
Nicotinamide Riboside
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Benefits
Ingredients
Ingredients
How it works
How it works
How to take it
How to take it
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The role of NR and NAD+ in aging
NR supplementation boosts NAD+ in humans
Benefits of NR – data from human studies
1. Yoshino J, Baur J, Imai S. NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR. Cell Metab. 2018 Mar; 27(3): 513-528
2. Fang E, Lautrup S, Hou Y, Demarest T, Croteau D, Mattson M, et al. NAD+ in Aging: Molecular Mechanisms and Translational Implications. Trends Mol Med. 2017 Oct; 23(10): 899-916.
3. Mehmel M, Jovanovic N, Spitz U. Nicotinamide Riboside—The Current State of Research and Therapeutic Uses. Nutrients .2020 Jun; 12(6): 1616.
4. Massudi H, Grant R, Braidy N, Guest J, Farnsworth B, Guillemin G. Age-Associated Changes In Oxidative Stress and NAD+ Metabolism In Human Tissue. Plos One [Internet]. 2012 Jul [cited 2023 Aug 24]; 7(7): e42357.
5. Aman Y, Qiu Y, Tao J, Fang E. Therapeutic potential of boosting NAD+ in aging and age-related diseases. Transl Med Aging. 2018 Jan; 2: 30-37.
6. Trammell S, Schmidt M, Weidemann B, Redpath P, Jaksch F, Dellinger R, et al. Nicotinamide riboside is uniquely and orally bioavailable in mice and humans. Nat Commun [Internet]. 2016 Oct [cited 2023 Aug 24]; 7: 12948.
7. Airhart S, Shireman L, Risler L, Anderson G, Gowda G, Raftery D, et al. An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers. Plos One [Internet]. 2017 Dec [cited 2023 Aug 24]; 12(12): e0186459.
8. Dellinger R, Santos S, Morris M, Evans M, Almanina D, Guarente L, et al. Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: a randomized, double-blind, placebo-controlled study. NPJ Aging Mech Dis. 2017 Nov; 3: 17.
9. Martens C, Denman B, Mazzo M, Armstrong M, Reisdorph N, McQueen M, et al. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. Nat Commun. 2018 Mar; 9(1): 1286.
10. Elhassan Y, Kluckova K, Fletcher R, Schmidt M, Garten A, Doig C, et al. Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures. Cell Rep. 2019 Aug; 28(7): 1717-1728
11. Lapatto H, Kuusela M, Heikkinen A, Muniandy M, van der Kolk M, Gopalakrishnan S. Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study. Sci Adv [Internet]. 2023 Jan [cited 2023 Aug 24]; 9(2): eadd5163. 10.1126/sciadv.add5163
12. Remie C, Roumans K, Moonen M, Connell N, Havekes B, Mevenkamp J, et al. Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans. Am J Clin Nutr. 2020 Aug; 112(2): 413-426.
13. Dolopikou C, Kourtzidis I, Margaritelis N, Vrabas I, Koidou I, Kyparos A, et al. Acute nicotinamide riboside supplementation improves redox homeostasis and exercise performance in old individuals: a double-blind cross-over study. Eur J Nutr. 2020 Mar; 59(2); 505-515.
14. Heilbronn L. Clinical Trials Corner. Nutr Healthy Aging. 2017 Mar; 4(2): 193-194.
15. Brakedal B, Dolle C, Riemer F, Ma Y, Nido G, Skeie G. The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson's disease. Cell Metab. 2022 Mar; 3483): 396-407.
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What's inside?
Science-backed ingredients
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3RD PARTY PURITY & QUALITY TESTED
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SCIENTIFICALLY-BACKED FORMULAS
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CAREFULLY MANUFACTORED IN BARCELONA
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NO GMO, NO FILLERS, NO JUNK
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HIGH QUALITY INGREDIENTS
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OPTIMIZED BIOAVAILABILITY
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- TCThomas C.Verified BuyerRated 5 out of 5 stars1 month agoI am satisfied with my purchase
The NR is certified by a German laboratory, which gives me confidence in its purity and content. The previous one I was taking did not work for me, and I think it is because it was not tested and could have less purity
- VViktorVerified ReviewerRated 5 out of 5 stars2 months agoErgänzung für einen Energieschub und eine schnellere Erholung
Nicotinamid-Ribosid (NR) ist ein Co-Enzym, das den Zellen hilft, Energie zu produzieren. Energie ist für viele Körperfunktionen notwendig, wie z. B. für den Stoffwechsel, den Muskelaufbau und die Muskelerholung.
Seitdem ich NR in mein Trainingsprogramm aufgenommen habe, habe ich eine Steigerung des Muskelaufbaus während des Trainings festgestellt und auch die Erholungszeit der Muskeln nach dem Training verkürzt.
- OSOriol Salat M.Verified BuyerRated 5 out of 5 stars11 seconds agoMejor precio del mercado para 90 capsulas
He incluido esta Nicotinamide Riboside en mi rutina por 3 razones: 1) Mejor Precio en el mercado por cápsula 2) Producto testado por laboratorio independiente 3) No hay additivos artificiales como en otros productos de la competencia
- MMarkVerified ReviewerRated 5 out of 5 stars1 month agoAn energy boost in the morning
The Nicotinamide Riboside supplement gives me a boost of energy to cope with everyday life.
- AAlinaVerified BuyerRated 5 out of 5 stars1 month agoNicotinamide Riboside rein
Ich mag, dass das Produkt von einem deutschen Labor zertifiziert ist, gibt es mehrere teurere Produkte ohne diese Zertifizierung. Glücklich mit dem Produkt, die Formel ist sehr rein, nur Nicotinamid Ribosid +99% Inhalt, keine anderen unnötigen Zusatzstoffe. Ich habe bereits abonniert