Nicotinamide Riboside
Nicotinamide Riboside
Best anti-aging supplement
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Benefits
Benefits
Ingredients
Ingredients
What is Nicotinamide Riboside and what is it used for?
What is Nicotinamide Riboside and what is it used for?
How should Nicotinamide Riboside be taken?
How should Nicotinamide Riboside be taken?
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Shipping
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Why Subscribe
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The role of NR and NAD+ in aging
NR supplementation boosts NAD+ in humans
Benefits of NR – data from human studies
1. Yoshino J, Baur J, Imai S. NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR. Cell Metab. 2018 Mar; 27(3): 513-528
2. Fang E, Lautrup S, Hou Y, Demarest T, Croteau D, Mattson M, et al. NAD+ in Aging: Molecular Mechanisms and Translational Implications. Trends Mol Med. 2017 Oct; 23(10): 899-916.
3. Mehmel M, Jovanovic N, Spitz U. Nicotinamide Riboside—The Current State of Research and Therapeutic Uses. Nutrients .2020 Jun; 12(6): 1616.
4. Massudi H, Grant R, Braidy N, Guest J, Farnsworth B, Guillemin G. Age-Associated Changes In Oxidative Stress and NAD+ Metabolism In Human Tissue. Plos One [Internet]. 2012 Jul [cited 2023 Aug 24]; 7(7): e42357.
5. Aman Y, Qiu Y, Tao J, Fang E. Therapeutic potential of boosting NAD+ in aging and age-related diseases. Transl Med Aging. 2018 Jan; 2: 30-37.
6. Trammell S, Schmidt M, Weidemann B, Redpath P, Jaksch F, Dellinger R, et al. Nicotinamide riboside is uniquely and orally bioavailable in mice and humans. Nat Commun [Internet]. 2016 Oct [cited 2023 Aug 24]; 7: 12948.
7. Airhart S, Shireman L, Risler L, Anderson G, Gowda G, Raftery D, et al. An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers. Plos One [Internet]. 2017 Dec [cited 2023 Aug 24]; 12(12): e0186459.
8. Dellinger R, Santos S, Morris M, Evans M, Almanina D, Guarente L, et al. Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: a randomized, double-blind, placebo-controlled study. NPJ Aging Mech Dis. 2017 Nov; 3: 17.
9. Martens C, Denman B, Mazzo M, Armstrong M, Reisdorph N, McQueen M, et al. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. Nat Commun. 2018 Mar; 9(1): 1286.
10. Elhassan Y, Kluckova K, Fletcher R, Schmidt M, Garten A, Doig C, et al. Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures. Cell Rep. 2019 Aug; 28(7): 1717-1728
11. Lapatto H, Kuusela M, Heikkinen A, Muniandy M, van der Kolk M, Gopalakrishnan S. Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study. Sci Adv [Internet]. 2023 Jan [cited 2023 Aug 24]; 9(2): eadd5163. 10.1126/sciadv.add5163
12. Remie C, Roumans K, Moonen M, Connell N, Havekes B, Mevenkamp J, et al. Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans. Am J Clin Nutr. 2020 Aug; 112(2): 413-426.
13. Dolopikou C, Kourtzidis I, Margaritelis N, Vrabas I, Koidou I, Kyparos A, et al. Acute nicotinamide riboside supplementation improves redox homeostasis and exercise performance in old individuals: a double-blind cross-over study. Eur J Nutr. 2020 Mar; 59(2); 505-515.
14. Heilbronn L. Clinical Trials Corner. Nutr Healthy Aging. 2017 Mar; 4(2): 193-194.
15. Brakedal B, Dolle C, Riemer F, Ma Y, Nido G, Skeie G. The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson's disease. Cell Metab. 2022 Mar; 3483): 396-407.
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Free from harmful fillers, artificial additives, and unnecessary preservatives.
Carefully Manufactured in Barcelona
in small batches under the strictest European restrictions of excellence
Science-backed ingredients
Our ingredients are standardized and tested to guarantee their active compound levels. We choose the most bioavailable and biologically active ingredient forms. Whenever possible, we source the best in class patented and fully traceable ingredients.
Nicotinamide Riboside
Our ingredients are standardized and tested to guarantee their active compound levels. We choose the most bioavailable and biologically active ingredient forms. Whenever possible, we source the best in class patented and fully traceable ingredients.